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MicroRNA Research to be Presented at Cedar Crest’s Annual Naomi Houser Lecture Series

2014 Naomi Houser Distinguished Biology Alumna Lecture
featuring Aimee Brown Jackson ‘89, Ph.D.
Tuesday, February 4 at 4 p.m.

Aimee Brown JacksonCedar Crest College will hold the 2014 Naomi Houser Distinguished Biology Alumna Lecture on Tuesday, Feb. 4 at 4 p.m., featuring the Director of Target Development at Miragen Therapeutics, Aimee Brown Jackson ‘89, Ph.D. Her lecture, “Discovery and Development of microRNA Therapeutics,” will take place in the Oberkotter Center immediately following a reception in Oberkotter Lounge at 3:15 p.m. The lecture is part of the annual Naomi House Lecture Series. The event is free and open to the public.

Jackson is the Director of Target Development at Miragen Therapeutics, a company focused on microRNA-based therapeutics. She has been working in the field of RNA interference and microRNAs for more than ten years and has authored or co-authored more than 20 publications in this area. Jackson received her Ph.D. from the University of Colorado Health Science Center and performed post-doctoral research at the University of Washington.

Upon completion of her post-doctoral training, Jackson joined Rosetta Inpharmatics/Merck in Seattle, where she established the use of expression profiling technologies combined with RNAi for target identification, target validation, elucidation of drug mechanism-of-action, and patient stratification. She was also part of a team investigating the therapeutic application of siRNAs. Jackson has published seminal research on the off-target effects of siRNAs, and methods to mitigate them, which inspired her current interest in the functions of microRNAs and their dysregulation in disease.

More recently, she has been investigating methods to annotate microRNA target regulation as a way to elucidate microRNA function and its role in disease. She is now pursuing therapeutic modulation of mircoRNA for impact on disease-associated gene networks. At Miragen, Jackson is leading the discovery and development of new therapeutic targets, as well as novel delivery technology for microRNA modulators.

The Naomi Houser Lecture Series was established in 1988 by the Alumnae Association to honor Miss Naomi Houser ‘21 who left a bequest to the Alumni Association. This series has given the Cedar Crest community the opportunity to learn about new medical research from leaders in varying medical fields for almost 30 years.