The Forensic Science Training Institute
at Cedar Crest College

June 24-26, 2009

Glen P. Jackson, Ph.D., Assistant Professor of Chemistry and Biochemistry and Interim Director of the Forensic Chemistry Program, Ohio University

When performed correctly, mass spectrometric analyses of forensic samples can provide evidence that is among the most reliable, specific and discriminatory of any other method. Although mass spectrometry is most commonly used to confirm the identification of suspected drug samples, it is finding an increasing number of new applications related to forensic science.

The first part of the course will provide a survey of the mature, novel and future applications of mass spectrometry in the different areas of forensic science, as well as providing a background perspective on the history and development of mass spectrometry. The second part of the course will focus on the interpretation of EI, CI, ESI and MALDI mass spectra. This course will develop the ability to understand, carry out and interpret mass spectrometric analyses. Experience with or previous knowledge of mass spectrometry is not required, but a solid scientific or technical background is preferred. The following topics will be covered:

1. Introduction and historical perspective of mass spectrometry, including the history of mass spectrometric evidence used in criminal and civil law.

2. Instrumentation. This will include a brief description of the different types of ion sources and mechanisms, mass analyzers/detectors and the types of applications for which each configuration is best suited.

3. Data acquisition/interpretation. This section will include a discussion on tandem mass spectrometers, hyphenated techniques and derivatization methods, especially regarding substances such as drugs of abuse.

4. Applications: these will include mature and novel applications such as drugs of abuse, sports testing, ignitable liquids, explosives, isotope ratio mass spectrometry, glass and polymer analysis, inks and paints, bullets and gunshot residues.

5. Interpretation of spectra: This section will include determination of molecular weight, chemical formulae, isotope peak ratio and ion charge states, identifying structural motifs/characteristic functionalities, understanding common fragmentation pathways and finding ways to confirm the determination results. Emphasis will be placed on common drugs of abuse, explosives and toxic compounds.

Students will be given sample spectra to manually interpret (in their own time) and present in class.

Registration Fee: $300.00
NEAFS Members Registration Only: January 19, 2009 - March 9, 2009
Full Registration: March 10, 2009 - June 10, 2009

Maximum Number of Registrants: 25 THIS WORKSHOP IS FULL